Prevnca Research

The Science Behind Prevnca

Prevnca is a plant-based (phyto-therapeutic) supplement developed to support cellular wellness and healthy immune function. It shares the research heritage of the Mamosure programme, drawing on the same commitment to botanical formulation backed by laboratory evaluation at reputed Indian research institutions.

Pre-Clinical Evaluation

The active botanical composition underlying our formulations has been studied in pre-clinical laboratory settings at government-affiliated research institutions, including ACTREC (Tata Memorial Centre, Navi Mumbai) and the Haffkine Institute for Training, Research and Testing (HITRT), Mumbai. These studies examined how the composition behaves at the cellular level and evaluated its safety profile against normal, healthy cells.

Areas of Study

  • Cellular wellness: Laboratory work investigating the composition's activity on cell populations.
  • Immune support: Evaluation of effects relevant to immune effector function.
  • Safety: Toxicological screening indicating the composition was non-toxic to normal, healthy cells in pre-clinical testing.

Patent-Protected Formulation

Prevnca is built on a proprietary, internationally patented composition — a Synergistic Composition with Anti-Proliferative Activity — with granted patents across multiple jurisdictions. See Our Patents for full details.

Important: These are pre-clinical laboratory findings and do not confirm equivalent effects in humans. Prevnca is a dietary supplement intended to support overall wellness and immunity. It is not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before use.
Pre-clinical research dossier

The science behind PREVNCA

A plant-based phyto-therapeutic formulation studied across immune, antioxidant, cellular and safety assays — evaluated in pre-clinical laboratory research at ACTREC (Tata Memorial Centre), the Haffkine Institute, and NABL-accredited laboratories.

ACTREC · Tata Memorial Centre
Haffkine Institute, Mumbai
NABL-accredited lab COA
10 completed studies
Mechanism of action

Four core pathways studied

Pathway 1

Oxidative stress

Reduces free-radical load and supports cellular protection.

Pathway 2

Immune regulation

Supports innate immunity and helps maintain immune balance.

Pathway 3

Detox support

Supports liver pathways and metabolic clearance (Ama reduction).

Pathway 4

Cellular signalling

Helps regulate abnormal cell-signalling pathways.

Key findings

What the studies observed

Every figure below is drawn from the completed pre-clinical assays. Values are laboratory measurements from cell-line or animal-model studies.

Immune cell activity · K562

Natural-killer cytotoxicity

% cytotoxicity by immune cells at 5:1 ratio, with vs without PREVNCA.

Untreated 26.98% ± 2.13 → Treated 97.98% ± 1.45.

Apoptosis · flow cytometry

Programmed cell death (cancer cell line)

Share of apoptotic cells, control vs treated.

Apoptotic fraction rose from ~4.9% to ~94% in the treated cell line.

Antioxidant · DPPH

Free-radical inhibition (dose response)

% inhibition across concentrations. IC50 = 0.112% v/v.

~90.9% inhibition at 1% v/v — comparable to high-dose ascorbic acid.

Inflammation · RT-PCR

Cytokine expression (fold change)

Treated vs control (control = 1.0-fold).

TNF-α 0.55 · IL-6 0.61 · IL-2 0.56 fold vs control.

DNA cell-cycle · apoptosis induction

Across three cancer cell lines

Apoptotic-cell percentage, control vs PREVNCA-treated, in pre-clinical cell-line studies.

Cell lineApoptosis — controlApoptosis — treatedChange
Head & neck (oral)0.34%23.17%▲ 68×
Triple-negative breast0.40%9.60%▲ 24×
Lung0.18%0.73%▲ 4×

Source: DNA cell-cycle (PI) analysis, ACTREC. Pre-clinical cell-line data.

Safety

Safety profile & quality

0

Mortality in rats

14-day toxicity study — no CNS/ANS side effects. Non-toxic and safe.

120–129%

Lymphocyte compatibility

Metabolic activity vs untreated (100%) — cyto-compatible to healthy lymphocytes.

2.4×

ROS in KB cells

Control 100% → Test 239.7%. Selective oxidative stress in cancer cell line.

NABL-accredited lab · certificate of analysis

Quality & purity

ParameterResultParameterResult
pH8.42 (alkaline) AflatoxinNot detected
Added sugarNil Lead<0.1 ppm
Arsenic<0.05 ppm Mercury<0.1 ppm
Total viable count<10 cfu Enterobacteria<10 cfu

Heavy-metal safe · microbial safe · aflatoxin free · no added sugar.

Clinical positioning.

PREVNCA is a plant-based food supplement developed to support immune balance, cellular health and everyday wellness. The research shown here is pre-clinical (laboratory cell-line and animal-model studies. Always consult your doctor.